Glucagonlike Peptide 2 Analogue Teduglutide
نویسندگان
چکیده
منابع مشابه
Glucagonlike peptide 1 analogs in diabetes care.
Bottom line Compared with placebo, semaglutide and liraglutide, but not lixisenatide, reduce cardiovascular disease (CVD) for about 1 in 50 patients with diabetes with existing CVD over 2 to 4 years, irrespective of specific hemoglobin A1c (HbA1c) targets. They reduce weight, but about 1 in 25 more patients than in the placebo group stopped treatment owing to gastrointestinal effects. Some unce...
متن کاملSMALL INTESTINE Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients
Background and aims: Glucagon-like peptide 2 (GLP-2) may improve intestinal absorption in short bowel syndrome (SBS) patients with an end jejunostomy. Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant GLP-2 analogue, prolongs the intestinotrophic properties of GLP-2 in animal models. The safety and effect of teduglutide were investigated in SBS patients with and without a colon in con...
متن کاملTeduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients.
BACKGROUND AND AIMS Glucagon-like peptide 2 (GLP-2) may improve intestinal absorption in short bowel syndrome (SBS) patients with an end jejunostomy. Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant GLP-2 analogue, prolongs the intestinotrophic properties of GLP-2 in animal models. The safety and effect of teduglutide were investigated in SBS patients with and without a colon in cont...
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ژورنال
عنوان ژورنال: JAMA Surgery
سال: 2013
ISSN: 2168-6254
DOI: 10.1001/jamasurg.2013.3731